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Drugs for Angiosarcoma

There are different ways chemotherapies work to stop your cells from dividing. Most affect cell cycle. Because they work differently, they also have different side effects. Some can be used together to have an even stronger effect. It’s important you discuss what to expect with your oncologist and infusion nurses.
If the tumor is fairly isolated, surgery may be an option.Radiation may also be used before, after, or during chemo. Biologics & small molecule inhibitors are a newer class of drugs which act on pathways which may be altered and lead to tumor growth.

This list includes some of the more commonly used chemotherapies your oncology team may use to stop the growth of Angiosarcoma. Angiosarcoma, particularly when once it’s metastatic (spread outside of the original site) is very hard to treat and permanently eradicate. This means there is not really a “standard of care” as much as trial and error process to see what may work best:

Anti-microtubule Drugs

Taxol (Paclitaxel)
Taxotere (Docetaxol)
Abraxane
Ixempra
Vinorelbine

Anti-vascular Agents

Avastin
Pazopanib

DNA Replication

Ifosfamide
Gemcitabine
Doxil (liposomal doxorubicin)
Doxorubicin\Adriamycin

Depending on the drug combination, you may receive steroids to counteract some of the harmful effects of chemo. Some of these infusions may take a couple hours, some can be given sequentially, while others you may have to return on separate days to receive.