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Why Clinical Trials?

Clinical trials are important treatment and research opportunities that stand to potentially benefit both individual angiosarcoma patients and the greater research community. In many cases, especially in rare cancers with no approved treatments, clinical trials may provide the most promising opportunity for an effective treatment.  Below, we provide some articles and resources which help explain clinical trials.

 

ARTICLES

The Importance of Clinical Trials 

This short,  easily understandable document addresses the importance of clinical trials. While written in 2011, Dr. Collins continues to hold the position of Director of the NIH, and is well-respected throughout the public health community.

 

Phases of Clinical Trials

The following synopsis comes from the MD Anderson Cancer Center in Houston, TX. Further detail describing each phase can be found on MDAnderson.org:

A new treatment goes through several phases. Each phase has a different purpose:

  • Phase I trials test if a new treatment is safe and look for the best way to give the treatment. Doctors also look for signs that cancer responds to the new treatment.
  • Phase II trials test if one type of cancer responds to the new treatment.
  • Phase III trials test if a new treatment is better than a standard treatment.
  • Phase IV trials find more information about long-term benefits and side effects.

 

Explaining the importance of clinical trials

Written by three Australian university academic researchers and published by the highly respected University of Queensland Faculty of Medicine, this article details and explains multiple facets of clinical trials and why each is important, such as randomization, placebo, control groups, and blinding.

 

A clinical trial saved my life. It could save yours, too.

Recently published as an Op-Ed in USA Today, this article was written by a rare cancer patient and advocate. He discusses the importance of clinical trials, and explains the necessity of trials in advancing medical breakthroughs through the lens of his personal experiences in an immunotherapy trial.

 

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RESOURCES

The following resources are additional portals of information; they are recommended by NORD, the National Organization for Rare Disorders, a nationally-renowned patient advocacy organization:

 

The Center for Information and Study on Clinical Research Participation (CISCRP) 

The Center for Information and Study on Clinical Research Participation (CISCRP) is an independent non-profit organization dedicated to educating and informing the public and patients about clinical research. CISCRP also provides information and resources to help research and health professionals better serve their patients and study volunteers.

 

CenterWatch

Founded in 1994, CenterWatch is a trusted source and global destination for clinical trials information for both professionals and patients.

 

ClinicalTrials.gov

Maintained by the NIH, ClinicalTrials.gov is a database of privately and publicly funded clinical studies conducted around the world. While we try to keep an updated list of relevant angiosarcoma clinical trials on this website, please visit this website to have a look around yourself.